Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 GeneticVariation UNIPROT

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 CausalMutation CGI

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.700 GenomicAlterations CGI

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.700 CausalMutation CGI

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 CausalMutation CGI

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 CausalMutation CGI

Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 CausalMutation CGI

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 CausalMutation CGI

Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GenomicAlterations CGI

Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.580 GenomicAlterations CGI

Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.580 CausalMutation CGI

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.550 CausalMutation CGI

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.500 CausalMutation CGI

Entrez Id: 894
Gene Symbol: CCND2
CCND2
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.310 GenomicAlterations CGI

Entrez Id: 253260
Gene Symbol: RICTOR
RICTOR
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 GenomicAlterations CGI

Entrez Id: 5885
Gene Symbol: RAD21
RAD21
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 CausalMutation CGI

Entrez Id: 6016
Gene Symbol: RIT1
RIT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.300 CausalMutation CGI

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Biomarker CTD_human DNA methylation markers and early recurrence in stage I lung cancer. 18337602

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Biomarker CTD_human Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent. 20727180

2010

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Biomarker CTD_human [Experimental study on combination of Ad-p53 with CDDP or As(2)O(3) in human lung adenocarcinoma cell line GLC-82]. 11798837

2000

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Therapeutic CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916

2015

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Biomarker CTD_human Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers. 17325666

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Therapeutic CTD_human [Experimental study on combination of Ad-p53 with CDDP or As(2)O(3) in human lung adenocarcinoma cell line GLC-82]. 11798837

2000

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Biomarker CTD_human Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer. 12115568

2002

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.800 Therapeutic CTD_human Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers. 17325666

2007